Fenton's reagent (FR) and the catabolic activity of Rhodococcus corallinus and Pseudomonas sp. strain D were combined to detoxify s-triazines in pure solutions and mixed wastes. In solutions containing only atrazine, complete atrazine decomposition was accomplished with 2.69 mM FR. But, FR treatment was not complete in a remediation context because stable, carcinogenic chlorinated products accumulated as end-products. R. corallinus degraded these products in ² 10 min and produced 47% 14CO2 from [2,4,6-14C]atrazine in 7 d. Combining R. corallinus with Pseudomonas sp. strain D increased 14CO2 production to 73%. When applied to a pesticide rinse water (PRW) containing atrazine, cyanazine, alachlor, metolachlor, and EPTC, ³ 99% of the pesticides were degraded with 12.2 mM FR. Subsequent treatment with R. corallinus and Pseudomonas sp. strain D degraded all chlorinated s-triazine intermediates and released 70% 14CO2 from an [2,4,6-14C]atrazine tracer in 10 d. Use of R. corallinus obviated the need for additional chemical pretreatment, e.g. acidification or base hydrolysis, used in previous studies prior to microbial incubations. Thus, this method has potential as an on-site treatment for PRW.