Contact Information
Phone: 608-263-4971
Fax: 608-265-2595
Email: joelpedersen@wisc.edu
Office: 103 Hiram Smith Annex
Program Affiliations
Molecular and Environmental Toxicology Center
Environmental Chemistry and Technology Program
Civil and Environmental Engineering
Biotechnology Training Program
Education
BS (Magna Cum Laude) Biological Sciences, 1988, Univ. of California Irvine
MS Environmental Engineering Science, 1990, California Institute of Technology
Dr Env Environmental Science and Engineering, 2001, Univ. of California Los Angeles
Teaching and Research
My research focuses on the behavior of organic toxicants in aquatic, soil and sediment systems with a particular emphasis on understanding the role played by natural organic matter in controlling their bioavailability, degradability and mobility. Major research interests include the behavior of and potential toxicity of pharmaceutically active compounds in the environment; the environmental persistence of prion proteins (the putative infectious agent in bovine spongiform encephalopathy (“mad cow” disease), chronic wasting disease of deer and elk and sheep scrapie); elucidation of molecular mechanisms responsible for sequestration and time-dependent decline in bioavailability of sediment- and soil-associated contaminants and the interaction of humic substances with mineral surfaces. Past work has focused on the effect of oxic state on the distribution and mobility of PCBs in estuarine sediments, and the characterization of organophosphorus insecticide phase distribution, flux and potential ecotoxicity in surface runoff.
Courses Taught
SS/MET/AHABS 606: Colloquium in Environmental Toxicology
MET/SS/CEE 631: Toxicants in the Environment
Current Grants
- NIH: The Impact of Microparticles on Oral TSE Infection
- NSF CAREER: Quantification of Prion Protein Sorption to Soil Components
- NSF: Prion Transport in Porous Media: Influence of Electrostatic and non-DLVO Interactions
- NSF Nanoscale Science and Engineering Center (NSEC): Research Thrust on Environmental Health and Safety Implications of Nanotechnology
- USDA CSREES: Inactivation of Prions During Composting
- USEPA STAR: Functionalized Engineered Metal Oxide Nanoparticles: Enlvironmental Transformations and Ecotoxicity
Publications
Liang, C., J.A. Pedersen, and T.C. Balser. 2009. Aminoglycoside antibiotics may interfere with microbial amino sugar analysis. J. Chromatogr. A. 1216:5296-5301.
Wiecinski, P.N., K.M. Metz, A.N. Mangham, K.H. Jacobson, R.J. Hamers, and J.A. Pedersen. 2009. Gastrointestinal biodurability of engineered nanomaterials: Development of in vitro assay. Nanotoxicol. 3:202-214. doi:10.1080/17435390902859556.
Johnson, C.J., P.U.P.A. Gilbert, D. McKenzie, J.A. Pedersen, and J.M. Aiken. 2009. Ultraviolet-ozone treatment reduces levels of disease-associated prion protein infectivity. BMC Res. Notes. 2:121-125.
Gao, J., J.A. Pedersen. 2010. Sorption of sulfonamide antimicrobial agents to humic-clay complexes. J. Environ. Qual. 39:000-000 (in press).
Jacobson, K.H., S. Lee, R.A. Somerville, D. McKenzie, C.H. Benson, and J.A. Pedersen. Pathogenic prion protein transport through soils. J. Environ. Qual. 39:000-000 (invited, accepted).
Seyfried, E.E., R.J. Newton, K.F. Rubert, IV, J.A. Pedersen, and K.D. McMahon. 200_. Diversity of tetracycline resistance genes in aquaculture facilities with varying use of oxytetracycline. Microb. Ecol. (revision submitted 10/21/09).
Jacobson, K.H., S. Lee, D. McKenzie, C.H. Benson, and J.A. Pedersen. 2009. Transport of the pathogenic prion protein through landfill materials. Environ. Sci. Technol. 43:2022-2028. doi:10.1021/es-2008-02632d.
Metz, K.M., A.N. Magham, M.J. Bierman, S. Jin, R.J. Hamers, and J.A. Pedersen. 2009. Engineered nanomaterial transformation under oxidative environmental conditions: Development of an in vitro biomimetic assay. Environ. Sci. Technol. 43:1598-1604. doi:10.1021/es02217y.
King Heiden, T.C., P.N. Wiecinski, A.N. Magham, K.M. Metz, D. Nesbit, J.A. Pedersen, R.J. Hamers, W. Heideman, and R.E. Peterson. 2009. Quantum dot nanotoxicity assessment using the zebrafish embryo. Environ. Sci. Technol. 43:1605-1611. doi:10.1021/es01925c.
Russo, F., C.J. Johnson, D. McKenzie, J.M. Aiken, and J.A. Pedersen. 2009. Degradation of the pathogenic prion protein by a manganese mineral found in soils. J. Gen. Virol. 90:275-280.
Hinckley, G.T., C.J. Johnson, K.H. Jacobson, D. McKenzie, J.M. Aiken, K.D. McMahon, and J.A. Pedersen. 2008. Persistence of pathogenic prion protein during simulated wastewater treatment processes. Environ. Sci. Technol. 42:5254-5259. doi:10.1021/es703186e.
Bialk, H.M., and J.A. Pedersen. 2008. NMR investigation of enzymatic coupling of sulfanomide antimicrobials with humic substances. Environ. Sci. Tehcnol. 42:106-112. doi:10.1021/es070779d.
Sibley, S.D., and J.A. Pedersen. 2008. Interaction of the macrolide antibiotic clarithromycin with dissolved humic acid. Environ. Sci. Technol. 42:422-428. doi.10.1021/es071467d.
Johnson, C.J., J.A. Pedersen, R.J. Chappell, D. McKenzie, J.M. Aiken. 2007. Oral transmissibility of prion disease is enhanced by binding to soil particles. PLoS Pathogens 3(7), e93. doi:10.1371/journal.ppat.0030093.
Ma, X., C.H. Benson, D. McKenzie, J.M. Aiken, J.A. Pedersen. 2007. Adsorption of pathogenic prion protein to quartz sand. Environ. Sci. Technol. 41:2324-2330. doi:10.1021/es062122i.
Bialk, H.M., C. Hedman, A. Castillo, J.A. Pedersen. 2007. Laccase-mediated Michael addition of 15N-sulfapyridine to a model humic constituent. Environ. Sci. Technol. 41:3593-3600. doi:10.1021/es0617338.
Soliman, M.; Pedersen, J.A.; Park, H.; Castaneda-Jimenez, A.; Stenstrom, M.K.; Suffet, I.H. 2007. Human pharmaceuticals, antioxidants and plasticizers in wastewater treatment plant and water reclamation plant effluents. Wat. Environ. Res. 79:156-167. doi:10.2175/106143006X111961.
Johnson, C.J.; Phillips, K.E.; Schramm, P.T.; McKenzie, D.; Aiken, J.M.; Pedersen, J.A. 2006. Prions adhere to soil minerals and remain infections. PLoS Pathogens 2006, 2 (4), e32.doi: 10.1371/journal.ppat.0020032.
Gu, C., K.G. Karthikeyan, S.D. Sibley, and J.A. Pedersen. 2007. Complexation of the antibiotic tetracycline with humic acid. Chemosphere 66:1494-1501. doi:10.1016/j.chemosphere.2006.08.028.
Rubert, K.F., IV, and J.A. Pedersen. 2006. Kinetics of oxytetracycline reaction with a hydrous manganese oxide. Environ. Sci. Technol. 40:7216-7221. doi:10.1021/es060357o.
Schramm, P.T., C.J. Johnson, D. McKenzie, J.M. Aiken, and J.A. Pedersen. 2006. Potential role of soil in the transmission of prion disease. Medical Mineralogy and Geochemistry. Rev. Mineral. Geochem. 64:135-152. doi:10.2138/rmg.2006.64.5.
Johnson, C.J., K.E. Phillips, P.T. Schramm, D. McKenzie, J.M. Aiken, and J.A. Pedersen. 2006. Prions adhere to soil minerals and remain infectious. PLoS Pathogens 2(4):296-302(e32). doi:10.1371/journal.ppat0020032.
Pedersen, J.A., Yeager, M.A., Suffet, I.H. 2006. Organophosphorus insecticides in agricultural and residential runoff: Field observations and implications for Total Maximum Daily Load development. Environ. Sci. Technol. 40:2120-2127. doi: 10.1021/es051677v.
Gao, J., Pedersen, J.A. 2005. Adsorption of sulfonamide antimicrobial agents to clay minerals. Environ. Sci. Tech. 39:9509-9516. doi: 10.1021/es50644c.
Bialk, H.M., Simpson, A.J., Pedersen, J.A. 2005. Cross-coupling of sulfonamide antimicrobial agents to model humic constituents. Environ. Sci. Tech. 39:4463-4473. doi: 10.1021/es0500916.
Pedersen, J.A., Soliman, M.A., Suffet, I.H. 2005. Human pharmaceuticals, hormones and personal care product ingredients in runoff from agricultural fields irrigated with treated wastewater. J. Agric. Food Chem. 53:1625-1632. doi: 10.1021/jf049228m.
Rose, P.E., Pedersen, J.A. 2005. Fate of oxytetracycline in streams receiving discharge from aquaculture facilities: Model simulations. Environ. Toxicol. Chem. 24(1):40-50.
Soliman, M.A.; Pedersen, J.A.; Suffet, I.H. Rapid gas chromatography-mass spectrometry screening method for human pharmaceuticals, hormones, antioxidants and plasticizers in water. 2004. J. Chromatogr. A 1029: 223-227.
Lin, C.-H.M., J.A. Pedersen, and I.H. Suffet. 2003. Influence of aeration on hydrophobic organic contaminant distribution and flux in estuarine sediments. Environ. Sci. Technol.37:3547-3554. doi: 10.1021/es026048p.
Pedersen, J.A., M.A. Yeager, and I.H. Suffet. 2003. Xenobiotic organic compounds in runoff from fields irrigated with treated wastewater. J. Agric. Food Chem. 51:1360-1372. doi: 10.1021/jf025953q.
Pedersen, J.A., M.A.Yeager, and I.H. Suffet. 2002. Characterization and mass load estimates of organic compounds from agricultural irrigation runoff . Wat. Sci. Technol. 45(9):103-110.
Pedersen, J.A., C.J. Gabelich, C.-H. Lin, and I.H. Suffet, I.H. 1999. Aeration effects on the partitioning of a PCB to anoxic estuarine sediment pore water dissolved organic matter. Environ. Sci. Technol. 33:1388-1397. doi:10.1021/es980717a.
Awards and Honors
2006-11 National Science Foundation Faculty Early Career Development (CAREER) Award
2006 Soil Science Society of America Early Career Professional Award
1998 Charles F. Scott Fellow (University of California, Los Angeles)
1995 Steve J. Sackler Scholar (University of California, Los Angeles)
1990 Hewlett Foundation Environmental Quality Laboratory Fellow (California Institute of Technology)
1987 Phi Beta Kappa (University of California, Irvine) |
