
Environmental organic and biophysical chemistry; behavior of organic chemicals, macromolecules and nanoparticles in terrestrial and aquatic environments.
Phone: 608.263.4971
Fax: 608.265.2595
Email: joelpedersen@wisc.edu
Office: 103 Hiram Smith Annex
2013
Jacobson, K.H.; Kuech, T.R.; Pedersen, J.A. Attachment of pathogenic prion protein to model mineral surfaces. Environ. Sci. Technol. 2013, 47 (in press). doi: 10.1021/es3045899
Bar-Ilan, O.; Chuang, C.C.; Schwahn, D.J.; Yang, S.; Joshi, S.; Pedersen, J.A.; Hamers, R.J.; Peterson, R.E.; Heideman, W. TiO2 nanoparticle exposure spanning zebrafish development: photo-dependent toxicity at parts per billion concentrations. Environ. Sci. Technol. 2013, 47, 4726-4733. doi: 10.1021/es304514r
Yang, S.; Louis, K.; Heideman, W.; Hamers, R.J.; Peterson, R.E.; Pedersen, J.A. Influence of humic acid on titanium dioxide nanoparticle toxicity to developing zebrafish. Environ. Sci. Technol. 2013, 47, 4718-4725. doi: 10.1021/es3047334
Booth, C.J.; Johnson, C.J.; Pedersen, J.A. Microbial and enzymatic inactivation of prions in soil environments. Soil Biol. Biochem. 2013, 59, 1-15. doi: 10.1016/j.soilbio.2012.12.016
Johnson, C.J.; Gilbert, PUPA; Albrecht, M.; Baldwin, K.L.; Pedersen, J.A.; Aiken, J.M.; McKenzie, D. Low copper and high manganese levels in prion plaques. Viruses 2013, 5, 654-662. doi:10.3390/v5020654
2012
Tomaszewski, J.E.; Madliger, M.; Pedersen, J.A.; Schwarzenbach, R.P.; Sander, M. Adsorption of insecticidal Cry1Ab protein to humic substances. 2. Influence of humic and fulvic acid charge and polarity characteristics. Environ. Sci. Technol. 2012, 46, 9932-9940. doi: 10.1021/es302248u
Gao, J.; Hedman, C.; Liu, C.; Guo, T.; Pedersen, J.A. Transformation of sulfamethazine by manganese oxide in aqueous solution. Environ. Sci. Technol. 2012, 46, 2642-2651. doi: 10.1021/es202492h
Bishop, L.M.; Yeager, J.C.; Chen, X.; Wheeler, J.N.; Torelli, M.D.; Benson, M.C.; Burke, S.D.; Pedersen, J.A.; Hamers, R.J. A citric acid-derived ligand for modular functionalization of metal oxide surfaces via “click” chemistry. Langmuir 2012, 28, 1322-1329. doi: 10.1021/la204145t
Sturm, R.M.; Kreitinger, G.; Booth, C.J.; Smith, L.M.; Pedersen, J.A.; Li, L. Absolute quantification of prion protein (90-231) using stable isotope-labeled chymotryptic peptide standards in a LC-MRM AQUA workflow. J. Am. Soc. Mass. Spectr. 2012, 23, 1522-1533. doi: 10.1007/s13361-012-0411-1
Johnson, C.J.; Aiken, J.M.; McKenzie, D.; Samuel, M.D.; Pedersen, J.A. Highly efficient amplification of chronic wasting disease agent by protein misfolding cyclic amplification with beads (PMCAb). PLoS ONE 2012, 7, e35383. doi: 10.1371/journal.pone.0035383
Walters, R.H.; Jacobson, K.H.; Pedersen, J.A.; Murphy, R.M. Analysis of the elongation kinetics of polyglutamine peptide fibrils: A quartz crystal microbalance with dissipation study. J. Molec. Biol. 2012, 421, 329-347. doi: 10.1016/j.jmb.2012.03.017
Bar-Ilan, O.; Louis, K.; Yang, S.; Pedersen, J.A.; Hamers, R.J.; Peterson, R.E.; Heideman, W. Titanium dioxide nanoparticles produce phototoxicity in the developing zebrafish. Nanotoxicol. 2012, 6, 670-679. doi: 10.3109/17435390.2011.604438
Pedersen, J.A.; Somerville, R. Why and how are TSEs sometimes spread via environmental routes? In Decontamination of Prions; Deslys, J.-P.; Pocchiari, M.; Reisner, D.; Somerville, R. (eds); Düsseldorf University Press: Düsseldorf, Germany, 2012; 19-37.
2011
Sibley, S.D.; Goldberg, T.L.; Pedersen, J.A. Detection of known and novel adenoviruses in cattle wastes by using broad-spectrum primers. Appl. Environ. Microbiol. 2011, 77, 5001-5008. doi: 10.1128/AEM.00625-11
Smith, C.B.; Booth, C.M.; Pedersen, J.A. Fate of prions in soils: A review. J. Environ. Qual. 2011, 40, 449-461. doi: 10.2134/jeq2010.0412
Pedersen, J.A.; Simpson, M.A.; Bockheim, J.G. Kumar, K. Characterization of soil organic carbon in drained thaw lake basins of arctic Alaska by NMR and FTIR photoacoustic spectroscopy. Org. Geochem. 2011, 42, 947-954. doi: 10.1016/j.orggeochem.2011.04.003
Johnson, C.J.; McKenzie, D.; Pedersen, J.A.; Aiken, J.M. Meat and bone meal and mineral feed additives may increase the risk of oral prion disease transmission. J. Toxicol. Environ. Health A 2011, 74, 161-166. doi: 10.1080/15287394.2011.529066
2010
Gao, J.; Pedersen, J.A. Sorption of sulfonamide antimicrobial agents to humic-clay complexes. J. Environ. Qual. 2010, 39,228-235. doi: 10.2134/jeq2008.0274
Seyfried, E.E.; Newton, R.J.; Rubert, K.F., IV; Pedersen, J.A.; McMahon, K.D. Diversity of tetracycline resistance genes in aquaculture facilities with varying use of oxytetracycline.Microb. Ecol. 2010, 59, 799-807. doi: 10.1007/s00248-009-9624-7
Jacobson, K.H.; Lee, S.; Somerville, R.A.; McKenzie, D.; Benson, C.H.; Pedersen, J.A. Pathogenic prion protein transport through soils. J. Environ. Qual. 2010, 39, 1145-1152.doi: 10.2134/jeq2009.0137
Adkin, A.L.; Matthews, D.; Hope, J.; Maddison, B.C.; Somerville, R.A.; Pedersen, J. Risk of escape of prions in gaseous emissions from on-farm processing vessels Vet. Rec. 2010,167, 28-29. doi: 10.1136/vr.c3158
Lowry, G.V.; Holtze, E.M.; Bernhardt, E.S.; Dionysiou, D.D.; Pedersen, J.A.; Wiesner, M.R.; Xing, B. Environmental occurrence, behavior and ecological effects of engineered nanomaterials. J. Environ. Qual.2010, 39, 1867-1874. doi: 10.2134/jeq2010.0297
Oleson T.A.; Sahai, N.; Pedersen, J.A. Electrostatic effects on deposition of multiple phospholipid bilayers at oxide surfaces. J. Colloid Interface Sci. 2010, 352, 327-36. doi: 10.1016/j.jcis.2010.08.057
2009
Jacobson, K.H.; Lee, S.; McKenzie, D.; Benson, C.H.; Pedersen, J.A. Transport of the pathogenic prion protein through landfill materials. Environ. Sci. Technol. 2009, 43, 2022-2028. doi: 10.1021/es802632d
Metz, K.M.; Magham, A.N.; Bierman, M.J.; Jin, S.; Hamers, R.J.; Pedersen, J.A. Engineered nanomaterial transformation under oxidative environmental conditions: Development of an in vitro biomimetic assay. Environ. Sci. Technol.2009, 43, 1598-1604. doi: 10.1021/es802217y
King Heiden, T.C.; Wiecinski, P.N.; Magham, A.N.; Metz, K.M.; Nesbit, D.; Pedersen, J.A.; Hamers, R.J.; Heideman, W.; Peterson, R.E. Quantum dot nanotoxicity assessment using the zebrafish embryo. Environ. Sci. Technol. 2009, 43, 1605-1611. doi: 10.1021/es801925c
Wiecinski, P.N.; Metz, K.M.; Mangham, A.N.; Jacobson, K.H.; Hamers, R.J.; Pedersen, J.A. Gastrointestinal biodurability of engineered nanomaterials: Development of an in vitro assay. Nanotoxicol. 2009, 3, 202-214. doi: 10.1080/17435390902859556
Liang, C.; Pedersen, J.A.; Balser, T.C. Aminoglycoside antibiotics may interfere with microbial amino sugar analysis. J. Chromatogr. A 2009, 1216, 5296-5301. doi: 10.1016/j.chroma.2009.05.010
Russo, F.; Johnson, C.J.; Johnson, C.J.; McKenzie, D.; Aiken, J.M.; Pedersen, J.A. Degradation of the pathogenic prion protein by a manganese mineral found in soils. J. Gen. Virol.2009, 90, 275-280. doi: 10.1099/vir.0.003251-0
Johnson, C.J.; Gilbert, P.U.P.A.; McKenzie, D.; Pedersen, J.A.; Aiken, J.M. Ultraviolet-ozone treatment reduces levels of disease-associated prion protein and prion infectivity. BMC Res. Notes 2009, 2, 121-125
2008
Sibley, S.D.; Pedersen, J.A. Interaction of the macrolide antimicrobial clarithromycin with dissolved humic acid. Environ. Sci. Technol. 2008, 42, 422-428. doi: 10.1021/es071467d
Bialk, H.M.; Pedersen, J.A. NMR investigation of enzymatic coupling of sulfonamide antimicrobials with humic substances. Environ. Sci. Technol. 2008, 42, 106-112. doi: 10.1021/es070779d
Hinckley, G.T.; Johnson, C.J.; Jacobson, K.H.; McKenzie, D.; Aiken, J.M.; McMahon, K.D.; Pedersen, J.A. Persistence of pathogenic prion protein during simulated wastewater treatment processes. Environ. Sci. Technol. 2008, 42, 5254-5259. doi: 10.1021/es703186e
2007
Johnson, C.J.; Pedersen, J.A.; Chappell, R.J.; McKenzie, D.; Aiken, J.M. Oral transmissibility of prion disease is enhanced by binding to soil particles. PLoS Pathogens2007, 3, 874-881 (e93). doi: 10.1371/journal.ppat.0030093
Bialk, H.M.; Hedman, C.; Castillo, A.; Pedersen, J.A. Laccase-mediated Michael addition of 15N-sulfapyridine to a model humic constituent. Environ. Sci. Technol. 2007, 41, 3593-3600. doi: 10.1021/es0617338
Ma, X.; Benson, C.H.; McKenzie, D; Aiken, J.M.; Pedersen, J.A. Adsorption of pathogenic prion protein to quartz sand. Environ. Sci. Technol. 2007, 41, 2324-2330. doi: 10.1021/es062122i
Gu, C.; Karthikeyan, K.G.; Sibley, S.D.; Pedersen, J.A. Complexation of the antibiotic tetracycline with humic acid. Chemosphere 2007, 66, 1494-1501. doi: 10.1016/j.chemosphere.2006.08.028
Soliman, M.; Pedersen, J.A.; Park, H.; Castaneda-Jimenez, A.; Stenstrom, M.K; Suffet, I.H. Human pharmaceuticals, antioxidants and plasticizers in wastewater treatment plant and water reclamation plant effluents. Wat. Environ. Res. 2007, 79, 156-167. doi: 10.2175/106143006X111961
2006
Johnson, C.J.; Phillips, K.E.; Schramm, P.T.; McKenzie, D.; Aiken, J.M.; Pedersen, J.A. Prions adhere to soil minerals and remain infectious. PLoS Pathogens 2006, 2, 296-302 (e32). doi: 10.1371/journal.ppat.0020032
Rubert, K.F., IV; Pedersen, J.A. Kinetics of oxytetracycline reaction with a hydrous manganese oxide. Environ. Sci. Technol. 2006, 40, 7216-7221. doi: 10.1021/es060357o
Pedersen, J.A.; Yeager, M.A.; Suffet, I.H. Organophosphorus insecticides in agricultural and residential runoff: Field observations and implications for Total Maximum Daily Load development. Environ. Sci. Technol. 2006, 40, 2120-2127. doi: 10.1021/es051677v
Schramm, P.T.; Johnson, C.J.; Mathews, N.E.; McKenzie, D.; Aiken, J.M.; Pedersen, J.A. Potential role of soil in the transmission of prion disease. Medical Mineralogy and Geochemistry. Rev. Mineral. Geochem. 2006, 64, 135-152. doi: 10.2138/rmg.2006.64.5
Pedersen, J.A.; McMahon, K.D.; Benson, C.H. Prions: Novel pathogens of environmental concern? J. Environ. Eng. 2006, 132, 967-969. doi: 10.1061/(ASCE)0733-9372(2006)132:9(967)
2005
Gao, J.; Pedersen, J.A. Adsorption of sulfonamide antimicrobial agents to clay minerals. Environ. Sci. Technol. 2005, 39,9509-9516. doi: 10.1021/es050644c
Bialk, H.M.; Simpson, A.J.; Pedersen, J.A. Cross-coupling of sulfonamide antimicrobial agents to model humic constituents. Environ. Sci. Technol. 2005, 39, 4436-4473. doi: 10.1021/es0500916
Pedersen, J.A.; Soliman, M.A.; Suffet, I.H. Human pharmaceuticals, hormones and personal care product ingredients in runoff from agricultural fields irrigated with treated wastewater. J. Agric. Food Chem. 2005, 53, 1625-1632. doi: 10.1021/jf049228m
Rose, P.E.; Pedersen, J.A. Fate of oxytetracycline in streams receiving aquaculture discharges: Model simulations. Environ. Toxicol. Chem.2005, 24, 40-50. doi: 10.1897/03-640.1
Prior to 2005
Soliman, M.A.; Pedersen, J.A.; Suffet, I.H. Rapid gas chromatography-mass spectrometry screening method for human pharmaceuticals, hormones, antioxidants and plasticizers in water. J. Chromatogr. A 2004, 1029, 223-227. 10.1016/j.chroma.2003.11.098
Lin, C.-H.M.; Pedersen, J.A.; Suffet, I.H. Influence of aeration on hydrophobic organic contaminant distribution and flux in estuarine sediments. Environ. Sci. Technol. 2003, 37, 3547-3554. 10.1021/es026048p
Pedersen, J.A.; Yeager, M.A.; Suffet, I.H. Xenobiotic organic compounds in runoff from fields irrigated with treated wastewater. J. Agric. Food Chem. 2003, 51, 1360-1372. 10.1021/jf025953q
Pedersen, J.A.; Schweitzer, L.E.; Lin, C.-H.; Suffet, I.H. Effect of oxic state on nonpolar organic contaminant distribution, mobility and bioavailability in estuarine sediments. Israel J. Chem. 2002, 42, 109-118. 10.1560/569Q-NH11-LXPM-KH1Q
Pedersen, J.A.; Yeager, M.A.; Suffet, I.H. Characterization and mass load estimates of organic compounds from agricultural irrigation runoff. Wat. Sci. Technol.2002, 45, 103-110.
Jones, K.B.; Heggem, D.T.; Wade, T.G.; Neale, A.C.; Ebert, D.W.; Nash, M.S.; Mehaffey, M.H.; Hermann, K.A.; Selle, A.R.; Augustine, S.; Goodman, I.A.; Pedersen, J.A.; Bolgrien, D.; Viger, J.M.; Chiang, D.; Lin, C.J.; Zhong, Y.; Baker, J.; Van Remortel, R.D. Assessing landscape condition relative to water resources in the western United States: a strategic approach. Environ. Monitor. Assess.2000, 64, 227-245. doi: 10.1023/A:1006448400047
Pedersen, J.A.; Gabelich, C.J.; Lin, C.-H.; Suffet, I.H. Aeration effects on the partitioning of a PCB to anoxic estuarine sediment pore water dissolved organic matter. Environ. Sci. Technol. 1999, 33, 1388-1397. 10.1021/es980717a
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